DOUBLE-STRANDED DNA IN EXOSOMES OF MALIGNANT PLEURAL EFFUSIONS AS A NOVEL DNA SOURCE FOR EGFR MUTATION DETECTION IN LUNG ADENOCARCINOMA

Double-Stranded DNA in Exosomes of Malignant Pleural Effusions as a Novel DNA Source for EGFR Mutation Detection in Lung Adenocarcinoma

Background: Exosomes are cell-derived vesicles and bear a specific set of nucleic acids including DNA (exoDNA).Thus, this study is to explore whether exoDNA in malignant pleural effusions (MPEs) could be a novel DNA source for mutation detection of epidermal growth factor receptor (EGFR).Methods: In this study, 52 lung adenocarcinoma patients were

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A Two-Channel Chinese Enterprise Abbreviation Generation Method Based on an Enterprise Component and Single-Character Strategy

The automatic generation of Chinese enterprise abbreviations is a task that extracts enterprise abbreviations to represent the enterprise full name.Traditional methods do not divide abbreviations in detail, which leads to a poor generation effect of irregular Chinese enterprise abbreviations generation, and the best selection method of candidate ab

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Upregulation of meiosis-specific genes in lymphoma cell lines following genotoxic insult and induction of mitotic catastrophe

Abstract Background We have previously reported that p53 mutated radioresistant lymphoma cell lines undergo mitotic catastrophe after irradiation, resulting in metaphase arrest and the generation of endopolyploid cells.A proportion of these endopolyploid cells then undergo a process of de-polyploidisation, stages of which are partially reminiscent

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